EGF protein (Pan troglodytes) - STRING interaction network

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EGF

Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)

Predicted Functional Partners:

EGFR

0.999

ERBB3

0.997

ERBB2

0.997

ERBB4

0.988

IGF1R

0.983

IGF1

0.975

PDGFRA

0.966

INSR

0.966

PDGFRB

0.966

KIT

0.955

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	EGFR	ENSPTRP00000028112	ENSPTRP00000069741	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	ERBB2	ENSPTRP00000028112	ENSPTRP00000069840	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.997
EGF	ERBB3	ENSPTRP00000028112	ENSPTRP00000008639	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian).	0.997
EGF	ERBB4	ENSPTRP00000028112	ENSPTRP00000063299	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.988
EGF	IGF1	ENSPTRP00000028112	ENSPTRP00000067917	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin-like growth factor 1 (Somatomedin C).	0.975
EGF	IGF1R	ENSPTRP00000028112	ENSPTRP00000012792	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.983
EGF	INSR	ENSPTRP00000028112	ENSPTRP00000063257	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.966
EGF	KIT	ENSPTRP00000028112	ENSPTRP00000027637	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.955
EGF	PDGFRA	ENSPTRP00000028112	ENSPTRP00000027635	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	T0011027 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.966
EGF	PDGFRB	ENSPTRP00000028112	ENSPTRP00000080188	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.966
EGFR	EGF	ENSPTRP00000069741	ENSPTRP00000028112	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	ERBB2	ENSPTRP00000069741	ENSPTRP00000069840	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
EGFR	ERBB3	ENSPTRP00000069741	ENSPTRP00000008639	Receptor protein-tyrosine kinase.	V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian).	0.998
EGFR	ERBB4	ENSPTRP00000069741	ENSPTRP00000063299	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.950
EGFR	IGF1	ENSPTRP00000069741	ENSPTRP00000067917	Receptor protein-tyrosine kinase.	Insulin-like growth factor 1 (Somatomedin C).	0.972
EGFR	IGF1R	ENSPTRP00000069741	ENSPTRP00000012792	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.891
EGFR	INSR	ENSPTRP00000069741	ENSPTRP00000063257	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.618
EGFR	PDGFRA	ENSPTRP00000069741	ENSPTRP00000027635	Receptor protein-tyrosine kinase.	T0011027 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.965
EGFR	PDGFRB	ENSPTRP00000069741	ENSPTRP00000080188	Receptor protein-tyrosine kinase.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.985
ERBB2	EGF	ENSPTRP00000069840	ENSPTRP00000028112	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.997

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