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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (247 aa)    
Predicted Functional Partners:
PM20D2
Peptidase M20 domain-containing protein 2; Belongs to the peptidase M20A family.
     
 0.886
PGR
Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
      
 0.738
PAQR8
Progestin and adipoQ receptor family member 8.
    
 
 0.652
PAQR7
Progestin and adipoQ receptor family member VII.
    
 
 0.619
PAQR5
Progestin and adipoQ receptor family member V.
    
 
 0.592
AAAS
Achalasia, adrenocortical insufficiency, alacrimia.
      
 0.572
FECH
Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 
 0.540
HOXA10
HOXA10 isoform 2.
      
 0.533
HOXA10-2
Homeobox A10.
      
 0.533
RHOG
Ras homolog gene family, member G (Rho G).
    
  0.518
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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