| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHSG | F2 | ENSPTRP00000027036 | ENSPTRP00000006168 | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.963 |
| AHSG | FGA | ENSPTRP00000027036 | ENSPTRP00000028386 | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | Fibrinogen alpha chain. | 0.975 |
| AHSG | FGB | ENSPTRP00000027036 | ENSPTRP00000028385 | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | Fibrinogen beta chain. | 0.943 |
| AHSG | FGG | ENSPTRP00000027036 | ENSPTRP00000083481 | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | Fibrinogen gamma chain. | 0.933 |
| AHSG | PLG | ENSPTRP00000027036 | ENSPTRP00000032051 | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.829 |
| AHSG | SERPINC1 | ENSPTRP00000027036 | ENSPTRP00000002829 | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | Serpin family C member 1; Belongs to the serpin family. | 0.884 |
| F2 | AHSG | ENSPTRP00000006168 | ENSPTRP00000027036 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | 0.963 |
| F2 | FGA | ENSPTRP00000006168 | ENSPTRP00000028386 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen alpha chain. | 0.993 |
| F2 | FGB | ENSPTRP00000006168 | ENSPTRP00000028385 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen beta chain. | 0.982 |
| F2 | FGG | ENSPTRP00000006168 | ENSPTRP00000083481 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Fibrinogen gamma chain. | 0.986 |
| F2 | ITGA2B | ENSPTRP00000006168 | ENSPTRP00000015779 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | ITGA2B isoform 3; Belongs to the integrin alpha chain family. | 0.608 |
| F2 | ITGB3 | ENSPTRP00000006168 | ENSPTRP00000068323 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Integrin beta-3 isoform X2. | 0.423 |
| F2 | PLG | ENSPTRP00000006168 | ENSPTRP00000032051 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.687 |
| F2 | SERPINC1 | ENSPTRP00000006168 | ENSPTRP00000002829 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family C member 1; Belongs to the serpin family. | 0.999 |
| FGA | AHSG | ENSPTRP00000028386 | ENSPTRP00000027036 | Fibrinogen alpha chain. | Alpha-2-HS-glycoprotein chain A; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (By similarity); Belongs to the fetuin family. | 0.975 |
| FGA | F2 | ENSPTRP00000028386 | ENSPTRP00000006168 | Fibrinogen alpha chain. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.993 |
| FGA | FGB | ENSPTRP00000028386 | ENSPTRP00000028385 | Fibrinogen alpha chain. | Fibrinogen beta chain. | 0.999 |
| FGA | FGG | ENSPTRP00000028386 | ENSPTRP00000083481 | Fibrinogen alpha chain. | Fibrinogen gamma chain. | 0.999 |
| FGA | ITGA2B | ENSPTRP00000028386 | ENSPTRP00000015779 | Fibrinogen alpha chain. | ITGA2B isoform 3; Belongs to the integrin alpha chain family. | 0.945 |
| FGA | ITGAM | ENSPTRP00000028386 | ENSPTRP00000013737 | Fibrinogen alpha chain. | Integrin subunit alpha M; Belongs to the integrin alpha chain family. | 0.935 |
