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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRATLecithin retinol acyltransferase. (230 aa)    
Predicted Functional Partners:
RPE65
Retinoid isomerohydrolase RPE65.
     
 0.983
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.979
RDH5
11-cis retinol dehydrogenase.
     
 0.954
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.954
RDH11
Retinol dehydrogenase 11 (All-trans/9-cis/11-cis); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.948
RDH8
RDH8 isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.937
DHRS3
Dehydrogenase/reductase (SDR family) member 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.933
DHRS9
DHRS9 isoform 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.929
RDH16
Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.925
ADH1A
Alcohol dehydrogenase 1A (class I), alpha polypeptide.
     
 0.918
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.