| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENPP1 | ENPP3 | ENSPTRP00000049619 | ENSPTRP00000084211 | ENPP1 isoform 1. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.919 |
| ENPP1 | GUCY1A1 | ENSPTRP00000049619 | ENSPTRP00000028399 | ENPP1 isoform 1. | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.900 |
| ENPP1 | GUCY1A2 | ENSPTRP00000049619 | ENSPTRP00000074354 | ENPP1 isoform 1. | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.900 |
| ENPP1 | GUCY1B1 | ENSPTRP00000049619 | ENSPTRP00000064068 | ENPP1 isoform 1. | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.911 |
| ENPP1 | LOC452727 | ENSPTRP00000049619 | ENSPTRP00000064202 | ENPP1 isoform 1. | Guanylate cyclase soluble subunit beta-2. | 0.911 |
| ENPP1 | NUDT2 | ENSPTRP00000049619 | ENSPTRP00000035706 | ENPP1 isoform 1. | Nudix (Nucleoside diphosphate linked moiety X)-type motif 2. | 0.917 |
| ENPP1 | PDE9A | ENSPTRP00000049619 | ENSPTRP00000024002 | ENPP1 isoform 1. | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its abi [...] | 0.679 |
| ENPP3 | ENPP1 | ENSPTRP00000084211 | ENSPTRP00000049619 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | ENPP1 isoform 1. | 0.919 |
| ENPP3 | GUCY1A1 | ENSPTRP00000084211 | ENSPTRP00000028399 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.900 |
| ENPP3 | GUCY1A2 | ENSPTRP00000084211 | ENSPTRP00000074354 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.900 |
| ENPP3 | GUCY1B1 | ENSPTRP00000084211 | ENSPTRP00000064068 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.911 |
| ENPP3 | LOC452727 | ENSPTRP00000084211 | ENSPTRP00000064202 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Guanylate cyclase soluble subunit beta-2. | 0.911 |
| ENPP3 | NUDT2 | ENSPTRP00000084211 | ENSPTRP00000035706 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | Nudix (Nucleoside diphosphate linked moiety X)-type motif 2. | 0.913 |
| ENPP3 | PDE9A | ENSPTRP00000084211 | ENSPTRP00000024002 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its abi [...] | 0.679 |
| GUCY1A1 | ENPP1 | ENSPTRP00000028399 | ENSPTRP00000049619 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | ENPP1 isoform 1. | 0.900 |
| GUCY1A1 | ENPP3 | ENSPTRP00000028399 | ENSPTRP00000084211 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.900 |
| GUCY1A1 | GUCY1A2 | ENSPTRP00000028399 | ENSPTRP00000074354 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.924 |
| GUCY1A1 | GUCY1B1 | ENSPTRP00000028399 | ENSPTRP00000064068 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.993 |
| GUCY1A1 | LOC452727 | ENSPTRP00000028399 | ENSPTRP00000064202 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Guanylate cyclase soluble subunit beta-2. | 0.998 |
| GUCY1A1 | NOS1 | ENSPTRP00000028399 | ENSPTRP00000092025 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | Nitric oxide synthase 1. | 0.909 |
