| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HSP90AA1 | HSP90AB1 | ENSPTRP00000070946 | ENSPTRP00000031135 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | HSP90AB1 isoform 1. | 0.999 |
| HSP90AA1 | LOC471721 | ENSPTRP00000070946 | ENSPTRP00000061079 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Voltage-dependent anion channel 2. | 0.503 |
| HSP90AA1 | PPID | ENSPTRP00000070946 | ENSPTRP00000028417 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Peptidylprolyl isomerase D. | 0.953 |
| HSP90AA1 | PPIF | ENSPTRP00000070946 | ENSPTRP00000004647 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.420 |
| HSP90AA1 | SLC25A5 | ENSPTRP00000070946 | ENSPTRP00000060483 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.474 |
| HSP90AA1 | VDAC1 | ENSPTRP00000070946 | ENSPTRP00000085752 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Voltage-dependent anion channel 1. | 0.456 |
| HSP90AB1 | HSP90AA1 | ENSPTRP00000031135 | ENSPTRP00000070946 | HSP90AB1 isoform 1. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.999 |
| HSP90AB1 | PPID | ENSPTRP00000031135 | ENSPTRP00000028417 | HSP90AB1 isoform 1. | Peptidylprolyl isomerase D. | 0.909 |
| HSP90AB1 | PPIF | ENSPTRP00000031135 | ENSPTRP00000004647 | HSP90AB1 isoform 1. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.418 |
| LOC471721 | HSP90AA1 | ENSPTRP00000061079 | ENSPTRP00000070946 | Voltage-dependent anion channel 2. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.503 |
| LOC471721 | PPID | ENSPTRP00000061079 | ENSPTRP00000028417 | Voltage-dependent anion channel 2. | Peptidylprolyl isomerase D. | 0.916 |
| LOC471721 | PPIF | ENSPTRP00000061079 | ENSPTRP00000004647 | Voltage-dependent anion channel 2. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.930 |
| LOC471721 | SLC25A31 | ENSPTRP00000061079 | ENSPTRP00000028217 | Voltage-dependent anion channel 2. | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.967 |
| LOC471721 | SLC25A4 | ENSPTRP00000061079 | ENSPTRP00000090035 | Voltage-dependent anion channel 2. | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.972 |
| LOC471721 | SLC25A5 | ENSPTRP00000061079 | ENSPTRP00000060483 | Voltage-dependent anion channel 2. | Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.986 |
| LOC471721 | SLC25A6 | ENSPTRP00000061079 | ENSPTRP00000063171 | Voltage-dependent anion channel 2. | Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.972 |
| LOC471721 | VDAC1 | ENSPTRP00000061079 | ENSPTRP00000085752 | Voltage-dependent anion channel 2. | Voltage-dependent anion channel 1. | 0.996 |
| LOC471721 | VDAC3 | ENSPTRP00000061079 | ENSPTRP00000074612 | Voltage-dependent anion channel 2. | Voltage dependent anion channel 3. | 0.997 |
| PPID | HSP90AA1 | ENSPTRP00000028417 | ENSPTRP00000070946 | Peptidylprolyl isomerase D. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.953 |
| PPID | HSP90AB1 | ENSPTRP00000028417 | ENSPTRP00000031135 | Peptidylprolyl isomerase D. | HSP90AB1 isoform 1. | 0.909 |
