close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1224 aa)    
Predicted Functional Partners:
CREB3
cAMP responsive element binding protein 3.
   
  
 0.772
PI15
Peptidase inhibitor 15; Belongs to the CRISP family.
   
  
 0.768
GPC2
GPC2 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
   
  
 0.765
ISLR
Immunoglobulin superfamily containing leucine rich repeat.
      
 0.764
PCDH7
PCDH7 isoform 7.
    
 
 0.729
CUBN
CUBN isoform 1.
      
 0.713
CREB3L1
cAMP responsive element binding protein 3-like 1.
      
 0.692
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
      
 0.683
EPHA3
EPH receptor A3.
    
 0.672
NID1
NID1 isoform 2.
    
 
 0.669
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.