RXFP3 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB2	RXFP3	ENSPTRP00000014687	ENSPTRP00000028769	ARRB2 isoform 2.	Relaxin family peptide receptor 3.	0.923
GNAI1	GNAI2	ENSPTRP00000071974	ENSPTRP00000025802	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	0.999
GNAI1	GNAI3	ENSPTRP00000071974	ENSPTRP00000001821	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.999
GNAI1	GNAO1	ENSPTRP00000071974	ENSPTRP00000088044	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	G protein subunit alpha o1.	0.894
GNAI1	RXFP1	ENSPTRP00000071974	ENSPTRP00000047055	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	RXFP1 isoform 5.	0.908
GNAI1	RXFP3	ENSPTRP00000071974	ENSPTRP00000028769	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Relaxin family peptide receptor 3.	0.936
GNAI1	RXFP4	ENSPTRP00000071974	ENSPTRP00000002435	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Relaxin family peptide/INSL5 receptor 4.	0.936
GNAI2	GNAI1	ENSPTRP00000025802	ENSPTRP00000071974	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.999
GNAI2	GNAI3	ENSPTRP00000025802	ENSPTRP00000001821	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.999
GNAI2	GNAO1	ENSPTRP00000025802	ENSPTRP00000088044	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	G protein subunit alpha o1.	0.972
GNAI2	INSL5	ENSPTRP00000025802	ENSPTRP00000001444	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	Insulin-like peptide INSL5 A chain; May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).	0.564
GNAI2	RLN3	ENSPTRP00000025802	ENSPTRP00000018051	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142) (By similarity).	0.577
GNAI2	RXFP1	ENSPTRP00000025802	ENSPTRP00000047055	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	RXFP1 isoform 5.	0.908
GNAI2	RXFP3	ENSPTRP00000025802	ENSPTRP00000028769	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	Relaxin family peptide receptor 3.	0.957
GNAI2	RXFP4	ENSPTRP00000025802	ENSPTRP00000002435	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	Relaxin family peptide/INSL5 receptor 4.	0.973
GNAI3	GNAI1	ENSPTRP00000001821	ENSPTRP00000071974	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.999
GNAI3	GNAI2	ENSPTRP00000001821	ENSPTRP00000025802	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.	0.999
GNAI3	GNAO1	ENSPTRP00000001821	ENSPTRP00000088044	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	G protein subunit alpha o1.	0.981
GNAI3	RXFP1	ENSPTRP00000001821	ENSPTRP00000047055	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	RXFP1 isoform 5.	0.908
GNAI3	RXFP3	ENSPTRP00000001821	ENSPTRP00000028769	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	Relaxin family peptide receptor 3.	0.936