STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UGT3A1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (523 aa)    
Predicted Functional Partners:
NAT2
N-acetyltransferase 2 (Arylamine N-acetyltransferase); Belongs to the arylamine N-acetyltransferase family.
   
  
 0.795
SLC35A2
SLC35A2 isoform 10.
      
 0.792
FMO3
Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...]
   
  
 0.763
EMB
EMB isoform 2.
   
  
 0.743
SLCO1A2
Solute carrier organic anion transporter family member.
   
    0.720
CWC25
CWC25 spliceosome-associated protein homolog.
   
    0.714
RUBCNL
Rubicon like autophagy enhancer.
   
    0.710
C1H1orf109
Chromosome 1 open reading frame 109.
   
    0.697
PGM2
Phosphoglucomutase 2.
   
    0.697
CYP3A5
CYP3A5 isoform 1.
   
 0.686
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.