C9 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

C9

Complement C9. (559 aa)

Predicted Functional Partners:

C6

0.998

C5

0.998

C7

0.997

C8B

0.939

C8G

0.932

VTN

0.824

C8A

0.814

C3

0.689

PTPN6

0.682

SERPINC1

0.667

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3	C5	ENSPTRP00000017648	ENSPTRP00000036418	Complement component 3.	Complement C5.	0.979
C3	C6	ENSPTRP00000017648	ENSPTRP00000028843	Complement component 3.	Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family.	0.645
C3	C7	ENSPTRP00000017648	ENSPTRP00000039456	Complement component 3.	Complement component 7.	0.699
C3	C9	ENSPTRP00000017648	ENSPTRP00000028833	Complement component 3.	Complement C9.	0.689
C3	SERPINC1	ENSPTRP00000017648	ENSPTRP00000002829	Complement component 3.	Serpin family C member 1; Belongs to the serpin family.	0.460
C3	VTN	ENSPTRP00000017648	ENSPTRP00000015217	Complement component 3.	VTN isoform 1.	0.645
C5	C3	ENSPTRP00000036418	ENSPTRP00000017648	Complement C5.	Complement component 3.	0.979
C5	C6	ENSPTRP00000036418	ENSPTRP00000028843	Complement C5.	Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family.	0.999
C5	C7	ENSPTRP00000036418	ENSPTRP00000039456	Complement C5.	Complement component 7.	0.998
C5	C8A	ENSPTRP00000036418	ENSPTRP00000046097	Complement C5.	C8A isoform 1.	0.677
C5	C8B	ENSPTRP00000036418	ENSPTRP00000093451	Complement C5.	C8B isoform 5.	0.933
C5	C8G	ENSPTRP00000036418	ENSPTRP00000036958	Complement C5.	Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family.	0.930
C5	C9	ENSPTRP00000036418	ENSPTRP00000028833	Complement C5.	Complement C9.	0.998
C5	SERPINC1	ENSPTRP00000036418	ENSPTRP00000002829	Complement C5.	Serpin family C member 1; Belongs to the serpin family.	0.546
C5	VTN	ENSPTRP00000036418	ENSPTRP00000015217	Complement C5.	VTN isoform 1.	0.799
C6	C3	ENSPTRP00000028843	ENSPTRP00000017648	Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family.	Complement component 3.	0.645
C6	C5	ENSPTRP00000028843	ENSPTRP00000036418	Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family.	Complement C5.	0.999
C6	C7	ENSPTRP00000028843	ENSPTRP00000039456	Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family.	Complement component 7.	0.998
C6	C8A	ENSPTRP00000028843	ENSPTRP00000046097	Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family.	C8A isoform 1.	0.771
C6	C8B	ENSPTRP00000028843	ENSPTRP00000093451	Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Belongs to the complement C6/C7/C8/C9 family.	C8B isoform 5.	0.945