GHR protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000061612	GH1	ENSPTRP00000061612	ENSPTRP00000016186	annotation not available	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	0.934
ENSPTRP00000061612	GH1-2	ENSPTRP00000061612	ENSPTRP00000054251	annotation not available	Chorionic somatomammotropin A2.	0.902
ENSPTRP00000061612	GHR	ENSPTRP00000061612	ENSPTRP00000074273	annotation not available	Growth hormone receptor.	0.983
ENSPTRP00000061612	JAK1	ENSPTRP00000061612	ENSPTRP00000001425	annotation not available	Tyrosine-protein kinase.	0.766
ENSPTRP00000061612	JAK2	ENSPTRP00000061612	ENSPTRP00000082180	annotation not available	Tyrosine-protein kinase.	0.848
ENSPTRP00000061612	LEPR	ENSPTRP00000061612	ENSPTRP00000059210	annotation not available	Leptin receptor.	0.679
ENSPTRP00000061612	PRL	ENSPTRP00000061612	ENSPTRP00000030340	annotation not available	PRL isoform 1.	0.975
ENSPTRP00000061612	PRLR	ENSPTRP00000061612	ENSPTRP00000028787	annotation not available	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.901
GH1	ENSPTRP00000061612	ENSPTRP00000016186	ENSPTRP00000061612	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	annotation not available	0.934
GH1	GH1-2	ENSPTRP00000016186	ENSPTRP00000054251	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	Chorionic somatomammotropin A2.	0.933
GH1	GHR	ENSPTRP00000016186	ENSPTRP00000074273	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	Growth hormone receptor.	0.995
GH1	JAK1	ENSPTRP00000016186	ENSPTRP00000001425	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	Tyrosine-protein kinase.	0.766
GH1	JAK2	ENSPTRP00000016186	ENSPTRP00000082180	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	Tyrosine-protein kinase.	0.852
GH1	LEPR	ENSPTRP00000016186	ENSPTRP00000059210	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	Leptin receptor.	0.684
GH1	PRL	ENSPTRP00000016186	ENSPTRP00000030340	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	PRL isoform 1.	0.977
GH1	PRLR	ENSPTRP00000016186	ENSPTRP00000028787	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.951
GH1-2	ENSPTRP00000061612	ENSPTRP00000054251	ENSPTRP00000061612	Chorionic somatomammotropin A2.	annotation not available	0.902
GH1-2	GH1	ENSPTRP00000054251	ENSPTRP00000016186	Chorionic somatomammotropin A2.	Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.	0.933
GH1-2	GHR	ENSPTRP00000054251	ENSPTRP00000074273	Chorionic somatomammotropin A2.	Growth hormone receptor.	0.983
GH1-2	JAK1	ENSPTRP00000054251	ENSPTRP00000001425	Chorionic somatomammotropin A2.	Tyrosine-protein kinase.	0.766