STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL15ARL15 isoform 1. (204 aa)    
Predicted Functional Partners:
ITSN2
ITSN2 isoform 1.
    
 0.787
MST1R
Macrophage stimulating 1 receptor.
   
 0.706
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
   
 0.706
ITSN1
ITSN1 isoform 4.
    
 0.681
ITSN1-2
ITSN1 isoform 7.
    
 0.681
LOC104003639
Guanine nucleotide-binding protein G(s) subunit alpha.
   
 0.659
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
    
 0.578
TOM1L1
Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family.
    
 0.558
TOM1
TOM1 isoform 7; Belongs to the TOM1 family.
    
 0.558
GGA3
Golgi-associated, gamma adaptin ear containing, ARF binding protein 3.
    
 0.558
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.