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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCC2Methylcrotonoyl-CoA carboxylase 2 (Beta). (563 aa)    
Predicted Functional Partners:
MCCC1
Methylcrotonoyl-CoA carboxylase 1 (Alpha).
 
 0.998
PCCA
Propionyl CoA carboxylase, alpha polypeptide.
 
 0.961
NELFCD
Negative elongation factor complex member C/D.
  
 0.923
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3); Belongs to the BCKDHA family.
  
 
 0.921
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 0.919
MCAT
Malonyl CoA:ACP acyltransferase (Mitochondrial).
  
 
 0.902
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase.
 
 0.882
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.
 
 0.877
GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.
  
 
  0.839
HPDL
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.831
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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