| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTSG | F2 | ENSPTRP00000010565 | ENSPTRP00000006168 | CTSG isoform 2; Belongs to the peptidase S1 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.481 |
| CTSG | F2RL2 | ENSPTRP00000010565 | ENSPTRP00000029118 | CTSG isoform 2; Belongs to the peptidase S1 family. | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | 0.699 |
| CTSG | F2RL3 | ENSPTRP00000010565 | ENSPTRP00000048931 | CTSG isoform 2; Belongs to the peptidase S1 family. | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.765 |
| ENSPTRP00000085459 | F2RL2 | ENSPTRP00000085459 | ENSPTRP00000029118 | annotation not available | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | 0.719 |
| ENSPTRP00000085459 | F2RL3 | ENSPTRP00000085459 | ENSPTRP00000048931 | annotation not available | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.760 |
| F2 | CTSG | ENSPTRP00000006168 | ENSPTRP00000010565 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | CTSG isoform 2; Belongs to the peptidase S1 family. | 0.481 |
| F2 | F2RL2 | ENSPTRP00000006168 | ENSPTRP00000029118 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | 0.933 |
| F2 | F2RL3 | ENSPTRP00000006168 | ENSPTRP00000048931 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.996 |
| F2 | PLG | ENSPTRP00000006168 | ENSPTRP00000032051 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.687 |
| F2RL2 | CTSG | ENSPTRP00000029118 | ENSPTRP00000010565 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | CTSG isoform 2; Belongs to the peptidase S1 family. | 0.699 |
| F2RL2 | ENSPTRP00000085459 | ENSPTRP00000029118 | ENSPTRP00000085459 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | annotation not available | 0.719 |
| F2RL2 | F2 | ENSPTRP00000029118 | ENSPTRP00000006168 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.933 |
| F2RL2 | F2RL3 | ENSPTRP00000029118 | ENSPTRP00000048931 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.949 |
| F2RL2 | GZMA | ENSPTRP00000029118 | ENSPTRP00000028899 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | GZMA isoform 1; Belongs to the peptidase S1 family. | 0.699 |
| F2RL2 | PLG | ENSPTRP00000029118 | ENSPTRP00000032051 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.699 |
| F2RL2 | PRSS1 | ENSPTRP00000029118 | ENSPTRP00000083064 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | Serine protease 1; Belongs to the peptidase S1 family. | 0.723 |
| F2RL2 | PRSS2 | ENSPTRP00000029118 | ENSPTRP00000063774 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | Serine protease 2; Belongs to the peptidase S1 family. | 0.723 |
| F2RL2 | PRSS3 | ENSPTRP00000029118 | ENSPTRP00000065505 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | PRSS3 isoform 2; Belongs to the peptidase S1 family. | 0.723 |
| F2RL2 | SORBS3 | ENSPTRP00000029118 | ENSPTRP00000034356 | Coagulation factor II (Thrombin) receptor-like 2; Belongs to the G-protein coupled receptor 1 family. | Sorbin and SH3 domain containing 3. | 0.581 |
| F2RL3 | CTSG | ENSPTRP00000048931 | ENSPTRP00000010565 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | CTSG isoform 2; Belongs to the peptidase S1 family. | 0.765 |
