F2R protein (Pan troglodytes) - STRING interaction network

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Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	F2	ENSPTRP00000003543	ENSPTRP00000006168	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.733
AGT	F2R	ENSPTRP00000003543	ENSPTRP00000029119	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	0.936
AGT	F2RL3	ENSPTRP00000003543	ENSPTRP00000048931	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.935
AGT	GNAQ	ENSPTRP00000003543	ENSPTRP00000049267	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Guanine nucleotide binding protein (G protein), q polypeptide.	0.518
AGT	LPAR1	ENSPTRP00000003543	ENSPTRP00000063334	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.920
AGT	LPAR2	ENSPTRP00000003543	ENSPTRP00000040364	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	Lysophosphatidic acid receptor 2.	0.917
CHRM2	F2R	ENSPTRP00000086632	ENSPTRP00000029119	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	0.913
CHRM2	GNAQ	ENSPTRP00000086632	ENSPTRP00000049267	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Guanine nucleotide binding protein (G protein), q polypeptide.	0.749
CHRM2	LPAR1	ENSPTRP00000086632	ENSPTRP00000063334	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.915
CHRM2	LPAR2	ENSPTRP00000086632	ENSPTRP00000040364	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	Lysophosphatidic acid receptor 2.	0.909
F2	AGT	ENSPTRP00000006168	ENSPTRP00000003543	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	0.733
F2	F2R	ENSPTRP00000006168	ENSPTRP00000029119	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	0.997
F2	F2RL3	ENSPTRP00000006168	ENSPTRP00000048931	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.996
F2	LPAR1	ENSPTRP00000006168	ENSPTRP00000063334	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.908
F2	LPAR2	ENSPTRP00000006168	ENSPTRP00000040364	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Lysophosphatidic acid receptor 2.	0.901
F2	PROCR	ENSPTRP00000006168	ENSPTRP00000052237	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Protein C receptor, endothelial.	0.910
F2R	AGT	ENSPTRP00000029119	ENSPTRP00000003543	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release.	0.936
F2R	CHRM2	ENSPTRP00000029119	ENSPTRP00000086632	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity). Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHR [...]	0.913
F2R	F2	ENSPTRP00000029119	ENSPTRP00000006168	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.997
F2R	F2RL3	ENSPTRP00000029119	ENSPTRP00000048931	Coagulation factor II (Thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.934