| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CREBBP | MED1 | ENSPTRP00000074980 | ENSPTRP00000015490 | CREB binding protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.762 |
| CREBBP | NCOA1 | ENSPTRP00000074980 | ENSPTRP00000020127 | CREB binding protein. | Nuclear receptor coactivator. | 0.997 |
| CREBBP | NCOA2 | ENSPTRP00000074980 | ENSPTRP00000069925 | CREB binding protein. | Nuclear receptor coactivator. | 0.998 |
| CREBBP | NCOR1 | ENSPTRP00000074980 | ENSPTRP00000075557 | CREB binding protein. | Nuclear receptor corepressor 1. | 0.813 |
| CREBBP | NR3C1 | ENSPTRP00000074980 | ENSPTRP00000029679 | CREB binding protein. | NR3C1 isoform 5. | 0.896 |
| CREBBP | NRIP1 | ENSPTRP00000074980 | ENSPTRP00000080348 | CREB binding protein. | Nuclear receptor interacting protein 1. | 0.645 |
| CREBBP | SMARCA4 | ENSPTRP00000074980 | ENSPTRP00000073124 | CREB binding protein. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. | 0.785 |
| FKBP5 | HSP90AA1 | ENSPTRP00000030899 | ENSPTRP00000070946 | Peptidylprolyl isomerase. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.970 |
| FKBP5 | NCOA2 | ENSPTRP00000030899 | ENSPTRP00000069925 | Peptidylprolyl isomerase. | Nuclear receptor coactivator. | 0.402 |
| FKBP5 | NR3C1 | ENSPTRP00000030899 | ENSPTRP00000029679 | Peptidylprolyl isomerase. | NR3C1 isoform 5. | 0.971 |
| FKBP5 | NR3C2 | ENSPTRP00000030899 | ENSPTRP00000057800 | Peptidylprolyl isomerase. | Nuclear receptor subfamily 3 group C member 2. | 0.811 |
| HSP90AA1 | FKBP5 | ENSPTRP00000070946 | ENSPTRP00000030899 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Peptidylprolyl isomerase. | 0.970 |
| HSP90AA1 | NR3C1 | ENSPTRP00000070946 | ENSPTRP00000029679 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | NR3C1 isoform 5. | 0.969 |
| HSP90AA1 | NR3C2 | ENSPTRP00000070946 | ENSPTRP00000057800 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | Nuclear receptor subfamily 3 group C member 2. | 0.438 |
| MED1 | CREBBP | ENSPTRP00000015490 | ENSPTRP00000074980 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | CREB binding protein. | 0.762 |
| MED1 | NCOA1 | ENSPTRP00000015490 | ENSPTRP00000020127 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.754 |
| MED1 | NCOA2 | ENSPTRP00000015490 | ENSPTRP00000069925 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.720 |
| MED1 | NCOR1 | ENSPTRP00000015490 | ENSPTRP00000075557 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 1. | 0.701 |
| MED1 | NR3C1 | ENSPTRP00000015490 | ENSPTRP00000029679 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | NR3C1 isoform 5. | 0.926 |
| MED1 | NR3C2 | ENSPTRP00000015490 | ENSPTRP00000057800 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 3 group C member 2. | 0.523 |
