TNIP1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IKBKG	LOC100610002	ENSPTRP00000082387	ENSPTRP00000076480	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	IKBKG isoform 9.	0.900
IKBKG	NFKB1	ENSPTRP00000082387	ENSPTRP00000028033	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.	0.995
IKBKG	NFKB2	ENSPTRP00000082387	ENSPTRP00000066154	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Nuclear factor kappa B subunit 2.	0.904
IKBKG	OPTN	ENSPTRP00000082387	ENSPTRP00000040385	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	OPTN isoform 1.	0.403
IKBKG	TNF	ENSPTRP00000082387	ENSPTRP00000069905	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.973
IKBKG	TNFAIP3	ENSPTRP00000082387	ENSPTRP00000031827	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Tumor necrosis factor, alpha-induced protein 3.	0.959
IKBKG	TNFRSF1A	ENSPTRP00000082387	ENSPTRP00000066030	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Tumor necrosis factor receptor superfamily, member 1A.	0.973
IKBKG	TNIP1	ENSPTRP00000082387	ENSPTRP00000076472	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNIP1 isoform 12.	0.851
IKBKG	UBC	ENSPTRP00000082387	ENSPTRP00000050925	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.939
LOC100610002	IKBKG	ENSPTRP00000076480	ENSPTRP00000082387	IKBKG isoform 9.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.900
LOC100610002	NFKB1	ENSPTRP00000076480	ENSPTRP00000028033	IKBKG isoform 9.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.	0.991
LOC100610002	NFKB2	ENSPTRP00000076480	ENSPTRP00000066154	IKBKG isoform 9.	Nuclear factor kappa B subunit 2.	0.842
LOC100610002	TNF	ENSPTRP00000076480	ENSPTRP00000069905	IKBKG isoform 9.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.931
LOC100610002	TNFAIP3	ENSPTRP00000076480	ENSPTRP00000031827	IKBKG isoform 9.	Tumor necrosis factor, alpha-induced protein 3.	0.887
LOC100610002	TNFRSF1A	ENSPTRP00000076480	ENSPTRP00000066030	IKBKG isoform 9.	Tumor necrosis factor receptor superfamily, member 1A.	0.916
LOC100610002	TNIP1	ENSPTRP00000076480	ENSPTRP00000076472	IKBKG isoform 9.	TNIP1 isoform 12.	0.773
LOC100610002	UBC	ENSPTRP00000076480	ENSPTRP00000050925	IKBKG isoform 9.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.802
MAP1LC3A	OPTN	ENSPTRP00000023008	ENSPTRP00000040385	Microtubule associated protein 1 light chain 3 alpha.	OPTN isoform 1.	0.975
MAP1LC3A	TNIP1	ENSPTRP00000023008	ENSPTRP00000076472	Microtubule associated protein 1 light chain 3 alpha.	TNIP1 isoform 12.	0.791
MAP1LC3A	UBC	ENSPTRP00000023008	ENSPTRP00000050925	Microtubule associated protein 1 light chain 3 alpha.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.777