close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D8TBC1 domain family member 8. (1155 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 
  0.898
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 
  0.589
YIPF6
Protein YIPF.
   
 
  0.481
SORT1
SORT1 isoform 2.
    
  0.473
IGF2R
IGF2R isoform 2.
   
 
  0.465
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 
  0.450
MIPOL1
Mirror-image polydactyly 1.
   
    0.449
HIP1R
Huntingtin interacting protein 1 related.
   
 
  0.441
OCRL
OCRL inositol polyphosphate-5-phosphatase.
   
 
 0.429
SNX9
Sorting nexin.
     
 0.425
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.