| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BIRC2 | CASP8 | ENSPTRP00000007251 | ENSPTRP00000021879 | Baculoviral IAP repeat containing 2. | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.914 |
| BIRC2 | FADD | ENSPTRP00000007251 | ENSPTRP00000006883 | Baculoviral IAP repeat containing 2. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.955 |
| BIRC2 | IKBKB | ENSPTRP00000007251 | ENSPTRP00000034600 | Baculoviral IAP repeat containing 2. | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. | 0.786 |
| BIRC2 | RIPK1 | ENSPTRP00000007251 | ENSPTRP00000030180 | Baculoviral IAP repeat containing 2. | Receptor (TNFRSF)-interacting serine-threonine kinase 1. | 0.997 |
| BIRC2 | RIPK3 | ENSPTRP00000007251 | ENSPTRP00000010556 | Baculoviral IAP repeat containing 2. | Receptor interacting serine/threonine kinase 3. | 0.967 |
| BIRC2 | TAB2 | ENSPTRP00000007251 | ENSPTRP00000031895 | Baculoviral IAP repeat containing 2. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.849 |
| BIRC2 | TNFRSF1A | ENSPTRP00000007251 | ENSPTRP00000066030 | Baculoviral IAP repeat containing 2. | Tumor necrosis factor receptor superfamily, member 1A. | 0.997 |
| BIRC2 | TRADD | ENSPTRP00000007251 | ENSPTRP00000046129 | Baculoviral IAP repeat containing 2. | TNFRSF1A-associated via death domain. | 0.994 |
| BIRC2 | TRAF2 | ENSPTRP00000007251 | ENSPTRP00000036949 | Baculoviral IAP repeat containing 2. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.997 |
| CASP8 | BIRC2 | ENSPTRP00000021879 | ENSPTRP00000007251 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | Baculoviral IAP repeat containing 2. | 0.914 |
| CASP8 | FADD | ENSPTRP00000021879 | ENSPTRP00000006883 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.999 |
| CASP8 | IKBKB | ENSPTRP00000021879 | ENSPTRP00000034600 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. | 0.812 |
| CASP8 | RIPK1 | ENSPTRP00000021879 | ENSPTRP00000030180 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | Receptor (TNFRSF)-interacting serine-threonine kinase 1. | 0.999 |
| CASP8 | RIPK3 | ENSPTRP00000021879 | ENSPTRP00000010556 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | Receptor interacting serine/threonine kinase 3. | 0.998 |
| CASP8 | TNFRSF1A | ENSPTRP00000021879 | ENSPTRP00000066030 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | Tumor necrosis factor receptor superfamily, member 1A. | 0.851 |
| CASP8 | TRADD | ENSPTRP00000021879 | ENSPTRP00000046129 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | TNFRSF1A-associated via death domain. | 0.998 |
| CASP8 | TRAF2 | ENSPTRP00000021879 | ENSPTRP00000036949 | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.974 |
| FADD | BIRC2 | ENSPTRP00000006883 | ENSPTRP00000007251 | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | Baculoviral IAP repeat containing 2. | 0.955 |
| FADD | CASP8 | ENSPTRP00000006883 | ENSPTRP00000021879 | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.999 |
| FADD | IKBKB | ENSPTRP00000006883 | ENSPTRP00000034600 | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta. | 0.553 |
