STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHX16Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Required for pre-mRNA splicing as component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily. (1050 aa)    
Predicted Functional Partners:
GPKOW
G-patch domain and KOW motifs.
   
 0.999
SF3B2
Splicing factor 3b, subunit 2, 145kDa.
   
 0.998
XAB2
XPA binding protein 2.
   
 0.997
DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38.
  
 
0.989
CWC22
CWC22 spliceosome-associated protein homolog.
   
 0.987
RNF113A
Ring finger protein 113A.
   
 0.986
CWC27
CWC27 spliceosome-associated protein homolog.
   
 0.985
CDC40
Cell division cycle 40 homolog.
   
 0.979
PPIL1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.974
PPIL2
Peptidylprolyl isomerase (Cyclophilin)-like 2.
   
 0.973
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.