STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PBX2Pre-B-cell leukemia homeobox 2. (430 aa)    
Predicted Functional Partners:
PKNOX1
PBX/knotted 1 homeobox 1.
    
0.948
MEIS2
MEIS2 isoform 1.
   
0.908
MAB21L1
MAB21L1 isoform 1.
    
 
 0.775
MEIS1
MEIS1 isoform 7.
   
0.738
GFRA2
GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
      
 0.733
MEIS3
MEIS3 isoform 5.
    
0.712
LMX1B
LIM homeobox transcription factor 1 beta.
    
 
 0.710
HOXC6
HOXC6 isoform 1.
    
 0.708
LRRC17
Leucine rich repeat containing 17.
      
 0.690
PKNOX2
PBX/knotted 1 homeobox 2.
    
0.666
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.