HLA-DQA2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BV7-9	HLA-DPA1	ENSPTRP00000082360	ENSPTRP00000030785	TRBV7-9 isoform 1.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.913
BV7-9	HLA-DPB1	ENSPTRP00000082360	ENSPTRP00000056904	TRBV7-9 isoform 1.	Major histocompatibility complex, class II, DP beta 1.	0.922
BV7-9	HLA-DQA2	ENSPTRP00000082360	ENSPTRP00000030767	TRBV7-9 isoform 1.	Major histocompatibility complex, class II, DQ alpha 2.	0.927
BV7-9	HLA-DQB1	ENSPTRP00000082360	ENSPTRP00000030768	TRBV7-9 isoform 1.	HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3.	0.922
BV7-9	LOC104006793	ENSPTRP00000082360	ENSPTRP00000054452	TRBV7-9 isoform 1.	HLA class II histocompatibility antigen, DR beta 3 chain precursor.	0.922
BV7-9	PATR-DMB	ENSPTRP00000082360	ENSPTRP00000030778	TRBV7-9 isoform 1.	HLA-DMB isoform 5.	0.902
BV7-9	PATR-DOB	ENSPTRP00000082360	ENSPTRP00000030772	TRBV7-9 isoform 1.	Patr class II histocompatibility antigen, DO beta chain; Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B- cells. Modifies peptide exchange activity of HLA-DM.	0.922
BV7-9	PATR-DRA	ENSPTRP00000082360	ENSPTRP00000030766	TRBV7-9 isoform 1.	MHC class II protein; Belongs to the MHC class II family.	0.931
CD74	HLA-DOA	ENSPTRP00000047911	ENSPTRP00000030784	CD74 isoform 5.	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	0.847
CD74	HLA-DPA1	ENSPTRP00000047911	ENSPTRP00000030785	CD74 isoform 5.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.953
CD74	HLA-DPB1	ENSPTRP00000047911	ENSPTRP00000056904	CD74 isoform 5.	Major histocompatibility complex, class II, DP beta 1.	0.906
CD74	HLA-DQA2	ENSPTRP00000047911	ENSPTRP00000030767	CD74 isoform 5.	Major histocompatibility complex, class II, DQ alpha 2.	0.978
CD74	HLA-DQB1	ENSPTRP00000047911	ENSPTRP00000030768	CD74 isoform 5.	HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3.	0.879
CD74	LOC104006793	ENSPTRP00000047911	ENSPTRP00000054452	CD74 isoform 5.	HLA class II histocompatibility antigen, DR beta 3 chain precursor.	0.867
CD74	PATR-DMB	ENSPTRP00000047911	ENSPTRP00000030778	CD74 isoform 5.	HLA-DMB isoform 5.	0.893
CD74	PATR-DOB	ENSPTRP00000047911	ENSPTRP00000030772	CD74 isoform 5.	Patr class II histocompatibility antigen, DO beta chain; Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B- cells. Modifies peptide exchange activity of HLA-DM.	0.867
CD74	PATR-DRA	ENSPTRP00000047911	ENSPTRP00000030766	CD74 isoform 5.	MHC class II protein; Belongs to the MHC class II family.	0.999
HLA-DOA	CD74	ENSPTRP00000030784	ENSPTRP00000047911	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	CD74 isoform 5.	0.847
HLA-DOA	HLA-DPA1	ENSPTRP00000030784	ENSPTRP00000030785	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.	0.988
HLA-DOA	HLA-DPB1	ENSPTRP00000030784	ENSPTRP00000056904	Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DP beta 1.	0.964