HLA-DQB1 protein (Pan troglodytes) - STRING interaction network

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Score

HLA-DQB1

HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3. (261 aa)

Predicted Functional Partners:

HLA-DQA1

0.997

CD74

0.973

INS

0.956

TRAC

0.954

HLA-DQA2

0.952

PATR-DRA

0.951

BV7-9

0.950

HCRT

0.949

CD4

0.946

PATR-DMB

0.926

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BV7-9	HLA-DQA1	ENSPTRP00000082360	ENSPTRP00000055403	TRBV7-9 isoform 1.	HLA-DQA2 isoform 1; Belongs to the MHC class II family.	0.928
BV7-9	HLA-DQB1	ENSPTRP00000082360	ENSPTRP00000030768	TRBV7-9 isoform 1.	HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3.	0.950
BV7-9	INS	ENSPTRP00000082360	ENSPTRP00000077843	TRBV7-9 isoform 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.702
BV7-9	PATR-DMB	ENSPTRP00000082360	ENSPTRP00000030778	TRBV7-9 isoform 1.	HLA-DMB isoform 5.	0.909
BV7-9	PATR-DRA	ENSPTRP00000082360	ENSPTRP00000030766	TRBV7-9 isoform 1.	MHC class II protein; Belongs to the MHC class II family.	0.976
BV7-9	TRAC	ENSPTRP00000082360	ENSPTRP00000080482	TRBV7-9 isoform 1.	TRAC isoform 1.	0.467
CD4	CD74	ENSPTRP00000054833	ENSPTRP00000047911	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	CD74 isoform 5.	0.584
CD4	HLA-DQA1	ENSPTRP00000054833	ENSPTRP00000055403	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	HLA-DQA2 isoform 1; Belongs to the MHC class II family.	0.927
CD4	HLA-DQB1	ENSPTRP00000054833	ENSPTRP00000030768	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3.	0.946
CD4	INS	ENSPTRP00000054833	ENSPTRP00000077843	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.655
CD4	PATR-DMB	ENSPTRP00000054833	ENSPTRP00000030778	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	HLA-DMB isoform 5.	0.908
CD4	PATR-DRA	ENSPTRP00000054833	ENSPTRP00000030766	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	MHC class II protein; Belongs to the MHC class II family.	0.946
CD4	TRAC	ENSPTRP00000054833	ENSPTRP00000080482	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	TRAC isoform 1.	0.407
CD74	CD4	ENSPTRP00000047911	ENSPTRP00000054833	CD74 isoform 5.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.584
CD74	HLA-DQA1	ENSPTRP00000047911	ENSPTRP00000055403	CD74 isoform 5.	HLA-DQA2 isoform 1; Belongs to the MHC class II family.	0.945
CD74	HLA-DQA2	ENSPTRP00000047911	ENSPTRP00000030767	CD74 isoform 5.	Major histocompatibility complex, class II, DQ alpha 2.	0.958
CD74	HLA-DQB1	ENSPTRP00000047911	ENSPTRP00000030768	CD74 isoform 5.	HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3.	0.973
CD74	PATR-DMB	ENSPTRP00000047911	ENSPTRP00000030778	CD74 isoform 5.	HLA-DMB isoform 5.	0.889
CD74	PATR-DRA	ENSPTRP00000047911	ENSPTRP00000030766	CD74 isoform 5.	MHC class II protein; Belongs to the MHC class II family.	0.994
HCRT	HLA-DQA1	ENSPTRP00000015664	ENSPTRP00000055403	Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.	HLA-DQA2 isoform 1; Belongs to the MHC class II family.	0.745