| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATRX | DAXX | ENSPTRP00000087577 | ENSPTRP00000030818 | Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...] | Death domain associated protein. | 0.998 |
| ATRX | PML | ENSPTRP00000087577 | ENSPTRP00000012429 | Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...] | PML isoform 6. | 0.475 |
| ATRX | TP53 | ENSPTRP00000087577 | ENSPTRP00000014836 | Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.852 |
| DAXX | ATRX | ENSPTRP00000030818 | ENSPTRP00000087577 | Death domain associated protein. | Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...] | 0.998 |
| DAXX | ENSPTRP00000083257 | ENSPTRP00000030818 | ENSPTRP00000083257 | Death domain associated protein. | annotation not available | 0.943 |
| DAXX | FAS | ENSPTRP00000030818 | ENSPTRP00000088261 | Death domain associated protein. | Fas (TNF receptor superfamily, member 6). | 0.992 |
| DAXX | HIPK2 | ENSPTRP00000030818 | ENSPTRP00000033846 | Death domain associated protein. | Homeodomain interacting protein kinase 2. | 0.929 |
| DAXX | MAP3K5 | ENSPTRP00000030818 | ENSPTRP00000043317 | Death domain associated protein. | Mitogen-activated protein kinase kinase kinase 5. | 0.995 |
| DAXX | PARK7 | ENSPTRP00000030818 | ENSPTRP00000078598 | Death domain associated protein. | PARK7 isoform 1. | 0.940 |
| DAXX | PML | ENSPTRP00000030818 | ENSPTRP00000012429 | Death domain associated protein. | PML isoform 6. | 0.991 |
| DAXX | TP53 | ENSPTRP00000030818 | ENSPTRP00000014836 | Death domain associated protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.994 |
| DAXX | UBE2I | ENSPTRP00000030818 | ENSPTRP00000012969 | Death domain associated protein. | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.950 |
| DAXX | USP7 | ENSPTRP00000030818 | ENSPTRP00000075972 | Death domain associated protein. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.979 |
| ENSPTRP00000083257 | DAXX | ENSPTRP00000083257 | ENSPTRP00000030818 | annotation not available | Death domain associated protein. | 0.943 |
| ENSPTRP00000083257 | PML | ENSPTRP00000083257 | ENSPTRP00000012429 | annotation not available | PML isoform 6. | 0.575 |
| ENSPTRP00000083257 | TP53 | ENSPTRP00000083257 | ENSPTRP00000014836 | annotation not available | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.903 |
| FAS | DAXX | ENSPTRP00000088261 | ENSPTRP00000030818 | Fas (TNF receptor superfamily, member 6). | Death domain associated protein. | 0.992 |
| FAS | MAP3K5 | ENSPTRP00000088261 | ENSPTRP00000043317 | Fas (TNF receptor superfamily, member 6). | Mitogen-activated protein kinase kinase kinase 5. | 0.809 |
| FAS | TP53 | ENSPTRP00000088261 | ENSPTRP00000014836 | Fas (TNF receptor superfamily, member 6). | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.707 |
| FAS | UBE2I | ENSPTRP00000088261 | ENSPTRP00000012969 | Fas (TNF receptor superfamily, member 6). | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.647 |
