STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRERF1Transcriptional regulating factor 1. (1219 aa)    
Predicted Functional Partners:
DNTTIP1
Deoxynucleotidyltransferase, terminal, interacting protein 1.
    
 
 0.898
ELMSAN1
ELMSAN1 isoform 5.
    
 
0.803
LOC748850
HDAC2 isoform 9.
    
 
 0.633
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.633
NR5A1
Nuclear receptor subfamily 5 group A member 1.
    
 
 0.574
BTBD8
KIAA1107 isoform 1.
  
     0.495
CCNG1
CCNG1 isoform 2; Belongs to the cyclin family.
      
 0.493
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 
 0.470
ENSPTRP00000069644
THAP domain-containing protein 5-like isoform X1.
  
 
   0.467
THAP5
THAP domain containing 5.
  
 
   0.463
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.