| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APEX2 | CUL9 | ENSPTRP00000037716 | ENSPTRP00000031087 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | CUL9 isoform 1; Belongs to the cullin family. | 0.702 |
| BIRC5 | CUL9 | ENSPTRP00000061768 | ENSPTRP00000031087 | Baculoviral IAP repeat containing 5. | CUL9 isoform 1; Belongs to the cullin family. | 0.643 |
| BIRC5 | RBX1 | ENSPTRP00000061768 | ENSPTRP00000024839 | Baculoviral IAP repeat containing 5. | Ring-box 1, E3 ubiquitin protein ligase. | 0.495 |
| BIRC5 | TP53 | ENSPTRP00000061768 | ENSPTRP00000014836 | Baculoviral IAP repeat containing 5. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.822 |
| BIRC5 | UBC | ENSPTRP00000061768 | ENSPTRP00000050925 | Baculoviral IAP repeat containing 5. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.523 |
| CK820_G0025552 | CUL9 | ENSPTRP00000074389 | ENSPTRP00000031087 | SZT2 isoform 2. | CUL9 isoform 1; Belongs to the cullin family. | 0.651 |
| CUL7 | CUL9 | ENSPTRP00000031071 | ENSPTRP00000031087 | CUL7 isoform 2; Belongs to the cullin family. | CUL9 isoform 1; Belongs to the cullin family. | 0.969 |
| CUL7 | ENSPTRP00000084393 | ENSPTRP00000031071 | ENSPTRP00000084393 | CUL7 isoform 2; Belongs to the cullin family. | annotation not available | 0.655 |
| CUL7 | NEDD8 | ENSPTRP00000031071 | ENSPTRP00000090523 | CUL7 isoform 2; Belongs to the cullin family. | Ubiquitin-like protein Nedd8. | 0.720 |
| CUL7 | RBX1 | ENSPTRP00000031071 | ENSPTRP00000024839 | CUL7 isoform 2; Belongs to the cullin family. | Ring-box 1, E3 ubiquitin protein ligase. | 0.996 |
| CUL7 | RNF7 | ENSPTRP00000031071 | ENSPTRP00000071278 | CUL7 isoform 2; Belongs to the cullin family. | Ring finger protein 7. | 0.768 |
| CUL7 | TP53 | ENSPTRP00000031071 | ENSPTRP00000014836 | CUL7 isoform 2; Belongs to the cullin family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.920 |
| CUL7 | UBC | ENSPTRP00000031071 | ENSPTRP00000050925 | CUL7 isoform 2; Belongs to the cullin family. | Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] | 0.535 |
| CUL9 | APEX2 | ENSPTRP00000031087 | ENSPTRP00000037716 | CUL9 isoform 1; Belongs to the cullin family. | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | 0.702 |
| CUL9 | BIRC5 | ENSPTRP00000031087 | ENSPTRP00000061768 | CUL9 isoform 1; Belongs to the cullin family. | Baculoviral IAP repeat containing 5. | 0.643 |
| CUL9 | CK820_G0025552 | ENSPTRP00000031087 | ENSPTRP00000074389 | CUL9 isoform 1; Belongs to the cullin family. | SZT2 isoform 2. | 0.651 |
| CUL9 | CUL7 | ENSPTRP00000031087 | ENSPTRP00000031071 | CUL9 isoform 1; Belongs to the cullin family. | CUL7 isoform 2; Belongs to the cullin family. | 0.969 |
| CUL9 | ENSPTRP00000084393 | ENSPTRP00000031087 | ENSPTRP00000084393 | CUL9 isoform 1; Belongs to the cullin family. | annotation not available | 0.837 |
| CUL9 | NEDD8 | ENSPTRP00000031087 | ENSPTRP00000090523 | CUL9 isoform 1; Belongs to the cullin family. | Ubiquitin-like protein Nedd8. | 0.837 |
| CUL9 | RBX1 | ENSPTRP00000031087 | ENSPTRP00000024839 | CUL9 isoform 1; Belongs to the cullin family. | Ring-box 1, E3 ubiquitin protein ligase. | 0.995 |
