Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHR | AIP | ENSPTRP00000032381 | ENSPTRP00000006820 | T0073207 isoform 1. | Peptidylprolyl isomerase. | 0.997 |
| AHR | HSP90AA1 | ENSPTRP00000032381 | ENSPTRP00000070946 | T0073207 isoform 1. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.983 |
| AHR | HSP90AB1 | ENSPTRP00000032381 | ENSPTRP00000031135 | T0073207 isoform 1. | HSP90AB1 isoform 1. | 0.997 |
| AIP | AHR | ENSPTRP00000006820 | ENSPTRP00000032381 | Peptidylprolyl isomerase. | T0073207 isoform 1. | 0.997 |
| AIP | HSP90AA1 | ENSPTRP00000006820 | ENSPTRP00000070946 | Peptidylprolyl isomerase. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.950 |
| AIP | HSP90AB1 | ENSPTRP00000006820 | ENSPTRP00000031135 | Peptidylprolyl isomerase. | HSP90AB1 isoform 1. | 0.998 |
| AKT1 | AR | ENSPTRP00000082849 | ENSPTRP00000076864 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.756 |
| AKT1 | CDC37 | ENSPTRP00000082849 | ENSPTRP00000017839 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | CDC37 isoform 2. | 0.894 |
| AKT1 | CDK4 | ENSPTRP00000082849 | ENSPTRP00000039845 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | 0.539 |
| AKT1 | HSP90AA1 | ENSPTRP00000082849 | ENSPTRP00000070946 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.999 |
| AKT1 | HSP90AB1 | ENSPTRP00000082849 | ENSPTRP00000031135 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | HSP90AB1 isoform 1. | 0.994 |
| AKT1 | MTOR | ENSPTRP00000082849 | ENSPTRP00000000280 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. | 0.997 |
| AKT1 | STUB1 | ENSPTRP00000082849 | ENSPTRP00000012898 | AKT1 isoform 3; Belongs to the protein kinase superfamily. | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase. | 0.685 |
| AR | AKT1 | ENSPTRP00000076864 | ENSPTRP00000082849 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | AKT1 isoform 3; Belongs to the protein kinase superfamily. | 0.756 |
| AR | CDC37 | ENSPTRP00000076864 | ENSPTRP00000017839 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | CDC37 isoform 2. | 0.441 |
| AR | CDK4 | ENSPTRP00000076864 | ENSPTRP00000039845 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. | 0.481 |
| AR | HSP90AA1 | ENSPTRP00000076864 | ENSPTRP00000070946 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] | 0.997 |
| AR | HSP90AB1 | ENSPTRP00000076864 | ENSPTRP00000031135 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | HSP90AB1 isoform 1. | 0.990 |
| AR | MTOR | ENSPTRP00000076864 | ENSPTRP00000000280 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. | 0.412 |
| AR | STUB1 | ENSPTRP00000076864 | ENSPTRP00000012898 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase. | 0.889 |
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