NT5E protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	ADA2	ENSPTRP00000073897	ENSPTRP00000049871	Adenosine deaminase.	Adenosine deaminase 2.	0.966
ADA	NT5E	ENSPTRP00000073897	ENSPTRP00000031424	Adenosine deaminase.	5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.	0.972
ADA	PNP	ENSPTRP00000073897	ENSPTRP00000010346	Adenosine deaminase.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.980
ADA	UPP2	ENSPTRP00000073897	ENSPTRP00000021460	Adenosine deaminase.	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.	0.409
ADA2	ADA	ENSPTRP00000049871	ENSPTRP00000073897	Adenosine deaminase 2.	Adenosine deaminase.	0.966
ADA2	NT5E	ENSPTRP00000049871	ENSPTRP00000031424	Adenosine deaminase 2.	5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.	0.962
ADA2	PNP	ENSPTRP00000049871	ENSPTRP00000010346	Adenosine deaminase 2.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.955
ENPP1	GMPR	ENSPTRP00000049619	ENSPTRP00000030306	ENPP1 isoform 1.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.900
ENPP1	GMPR2	ENSPTRP00000049619	ENSPTRP00000010538	ENPP1 isoform 1.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.900
ENPP1	NT5E	ENSPTRP00000049619	ENSPTRP00000031424	ENPP1 isoform 1.	5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.	0.963
ENPP1	NUDT12	ENSPTRP00000049619	ENSPTRP00000090592	ENPP1 isoform 1.	Nudix (Nucleoside diphosphate linked moiety X)-type motif 12.	0.908
ENPP1	NUDT13	ENSPTRP00000049619	ENSPTRP00000042255	ENPP1 isoform 1.	Nudix (Nucleoside diphosphate linked moiety X)-type motif 13.	0.905
GMPR	ENPP1	ENSPTRP00000030306	ENSPTRP00000049619	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	ENPP1 isoform 1.	0.900
GMPR	GMPR2	ENSPTRP00000030306	ENSPTRP00000010538	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.994
GMPR	NT5E	ENSPTRP00000030306	ENSPTRP00000031424	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.	0.960
GMPR	PNP	ENSPTRP00000030306	ENSPTRP00000010346	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.469
GMPR	UPP2	ENSPTRP00000030306	ENSPTRP00000021460	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.	0.447
GMPR2	ENPP1	ENSPTRP00000010538	ENSPTRP00000049619	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	ENPP1 isoform 1.	0.900
GMPR2	GMPR	ENSPTRP00000010538	ENSPTRP00000030306	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.994
GMPR2	NT5E	ENSPTRP00000010538	ENSPTRP00000031424	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.	0.960