STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPACA1Sperm acrosome associated 1. (294 aa)    
Predicted Functional Partners:
ZPBP
Zona pellucida binding protein.
      
 0.654
IZUMO1
Izumo sperm-egg fusion 1.
      
 0.545
SPESP1
Sperm equatorial segment protein 1.
      
 0.504
SPAM1
Hyaluronidase.
   
  
 0.471
DPY19L2
DPY19L2 isoform 1.
      
 0.469
ENSPTRP00000079293
annotation not available
      
 0.469
SPACA3
Sperm acrosome membrane-associated protein 3, processed form; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N- acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity); Belongs to the glycosyl hydrolase 22 family.
      
 0.465
SPATA16
Spermatogenesis associated protein 16.
      
 0.461
SSMEM1
SSMEM1 isoform 1.
      
 0.457
SPACA4
Sperm acrosome associated 4.
      
 0.457
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.