STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3130 aa)    
Predicted Functional Partners:
MAD2L2
MAD2 mitotic arrest deficient-like 2.
    
 0.999
REV1
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
   
 0.998
POLD2-2
DNA polymerase delta 2, accessory subunit.
   
 0.974
POLD2
DNA polymerase delta 2, accessory subunit.
   
 0.963
PRIM2
PRIM2 isoform 1.
   
 0.953
POLA2
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.951
PRIM1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.950
POLH
Polymerase (DNA directed), eta.
   
 0.944
POLD3
Polymerase (DNA-directed), delta 3, accessory subunit.
   
 0.920
POLE3
Polymerase (DNA directed), epsilon 3 (P17 subunit).
   
 0.918
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.