STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRKTyrosine-protein kinase. (505 aa)    
Predicted Functional Partners:
MIPOL1
Mirror-image polydactyly 1.
   
  
 0.999
KIAA1328
KIAA1328 isoform 2.
   
    0.923
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.907
ENSPTRP00000093022
annotation not available
    
 0.905
ADAMTSL3
ADAMTSL3 isoform 1.
   
  0.806
BNIP2
BNIP2 isoform 1.
    
  0.749
COL10A1
Collagen type X alpha 1 chain.
 
  
 0.721
ENSPTRP00000093926
annotation not available
   
    0.698
COL15A1
COL15A1 isoform 2.
      
 0.684
CSK
Tyrosine-protein kinase.
  
0.666
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.