GOPC protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	GOPC	ENSPTRP00000025987	ENSPTRP00000031667	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	T0001380 isoform 1.	0.652
CFTR	ENSPTRP00000074085	ENSPTRP00000033597	ENSPTRP00000074085	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	annotation not available	0.457
CFTR	ENSPTRP00000085929	ENSPTRP00000033597	ENSPTRP00000085929	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	annotation not available	0.457
CFTR	GOPC	ENSPTRP00000033597	ENSPTRP00000031667	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	T0001380 isoform 1.	0.970
CFTR	RHOJ	ENSPTRP00000033597	ENSPTRP00000010893	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Ras homolog gene family, member J.	0.415
CFTR	RHOQ	ENSPTRP00000033597	ENSPTRP00000079929	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Ras homolog gene family, member Q.	0.457
ENSPTRP00000074085	CFTR	ENSPTRP00000074085	ENSPTRP00000033597	annotation not available	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.457
ENSPTRP00000074085	GOPC	ENSPTRP00000074085	ENSPTRP00000031667	annotation not available	T0001380 isoform 1.	0.772
ENSPTRP00000074085	RHOJ	ENSPTRP00000074085	ENSPTRP00000010893	annotation not available	Ras homolog gene family, member J.	0.843
ENSPTRP00000085929	CFTR	ENSPTRP00000085929	ENSPTRP00000033597	annotation not available	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.457
ENSPTRP00000085929	GOPC	ENSPTRP00000085929	ENSPTRP00000031667	annotation not available	T0001380 isoform 1.	0.772
ENSPTRP00000085929	RHOJ	ENSPTRP00000085929	ENSPTRP00000010893	annotation not available	Ras homolog gene family, member J.	0.843
GOPC	APPL1	ENSPTRP00000031667	ENSPTRP00000025987	T0001380 isoform 1.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.652
GOPC	CFTR	ENSPTRP00000031667	ENSPTRP00000033597	T0001380 isoform 1.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.970
GOPC	ENSPTRP00000074085	ENSPTRP00000031667	ENSPTRP00000074085	T0001380 isoform 1.	annotation not available	0.772
GOPC	ENSPTRP00000085929	ENSPTRP00000031667	ENSPTRP00000085929	T0001380 isoform 1.	annotation not available	0.772
GOPC	PICK1	ENSPTRP00000031667	ENSPTRP00000024729	T0001380 isoform 1.	Protein interacting with PRKCA 1.	0.637
GOPC	RHOJ	ENSPTRP00000031667	ENSPTRP00000010893	T0001380 isoform 1.	Ras homolog gene family, member J.	0.640
GOPC	RHOQ	ENSPTRP00000031667	ENSPTRP00000079929	T0001380 isoform 1.	Ras homolog gene family, member Q.	0.772
GOPC	ROS1	ENSPTRP00000031667	ENSPTRP00000080823	T0001380 isoform 1.	Proto-oncogene tyrosine-protein kinase ROS isoform X5.	0.628