close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REPS1RALBP1 associated Eps domain containing 1. (796 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.970
AAK1
AP2 associated kinase 1.
    
 0.966
ITSN2
ITSN2 isoform 1.
   
0.928
ITSN1
ITSN1 isoform 4.
   
0.918
ITSN1-2
ITSN1 isoform 7.
   
0.918
SGIP1
SH3 domain GRB2 like endophilin interacting protein 1.
    
 0.885
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
0.880
RALBP1
RalA binding protein 1.
    
 
 0.872
ENSPTRP00000092300
annotation not available
    
 
 0.872
BMP2K
BMP2 inducible kinase.
    
 0.844
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.