| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATIC | DHFR2 | ENSPTRP00000041425 | ENSPTRP00000091206 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | DHFR2 isoform 2. | 0.937 |
| ATIC | FTCD | ENSPTRP00000041425 | ENSPTRP00000069479 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | FTCD isoform 4. | 0.928 |
| ATIC | GART | ENSPTRP00000041425 | ENSPTRP00000045223 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ATIC | GART-2 | ENSPTRP00000041425 | ENSPTRP00000083097 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | annotation not available | 0.994 |
| ATIC | MTFMT | ENSPTRP00000041425 | ENSPTRP00000012255 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Mitochondrial methionyl-tRNA formyltransferase. | 0.935 |
| ATIC | MTHFD1L | ENSPTRP00000041425 | ENSPTRP00000031922 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like. | 0.980 |
| ATIC | MTHFD2L | ENSPTRP00000041425 | ENSPTRP00000070770 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 0.963 |
| ATIC | MTR | ENSPTRP00000041425 | ENSPTRP00000051007 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.927 |
| ATIC | SHMT1 | ENSPTRP00000041425 | ENSPTRP00000076664 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Serine hydroxymethyltransferase 1. | 0.981 |
| ATIC | SHMT2 | ENSPTRP00000041425 | ENSPTRP00000063004 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.981 |
| DHFR2 | ATIC | ENSPTRP00000091206 | ENSPTRP00000041425 | DHFR2 isoform 2. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.937 |
| DHFR2 | FTCD | ENSPTRP00000091206 | ENSPTRP00000069479 | DHFR2 isoform 2. | FTCD isoform 4. | 0.923 |
| DHFR2 | GART | ENSPTRP00000091206 | ENSPTRP00000045223 | DHFR2 isoform 2. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.955 |
| DHFR2 | GART-2 | ENSPTRP00000091206 | ENSPTRP00000083097 | DHFR2 isoform 2. | annotation not available | 0.573 |
| DHFR2 | MTFMT | ENSPTRP00000091206 | ENSPTRP00000012255 | DHFR2 isoform 2. | Mitochondrial methionyl-tRNA formyltransferase. | 0.689 |
| DHFR2 | MTHFD1L | ENSPTRP00000091206 | ENSPTRP00000031922 | DHFR2 isoform 2. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like. | 0.958 |
| DHFR2 | MTHFD2L | ENSPTRP00000091206 | ENSPTRP00000070770 | DHFR2 isoform 2. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 0.492 |
| DHFR2 | MTR | ENSPTRP00000091206 | ENSPTRP00000051007 | DHFR2 isoform 2. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.938 |
| DHFR2 | SHMT1 | ENSPTRP00000091206 | ENSPTRP00000076664 | DHFR2 isoform 2. | Serine hydroxymethyltransferase 1. | 0.972 |
| DHFR2 | SHMT2 | ENSPTRP00000091206 | ENSPTRP00000063004 | DHFR2 isoform 2. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.972 |
