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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOX3NADPH oxidase 3. (568 aa)    
Predicted Functional Partners:
CYBA
Cytochrome b-245 alpha chain.
   
 0.994
NOXA1
NOXA1 isoform 2.
   
 0.955
NOX4
NADPH oxidase 4.
  
 
0.945
NCF1
Neutrophil cytosolic factor 1.
   
 0.941
ENSPTRP00000084892
annotation not available
   
 0.941
DUOX1
DUOX1 isoform 1.
     
0.919
NOX4-2
NADPH oxidase 4.
  
 
0.911
NOX1
NADPH oxidase 1.
  
  
0.906
CYBB
Cytochrome b-245 beta chain.
  
  
0.903
NCF2
Neutrophil cytosolic factor 2.
   
 0.898
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.