| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C3 | FGA | ENSPTRP00000017648 | ENSPTRP00000028386 | Complement component 3. | Fibrinogen alpha chain. | 0.762 |
| C3 | FGB | ENSPTRP00000017648 | ENSPTRP00000028385 | Complement component 3. | Fibrinogen beta chain. | 0.515 |
| C3 | PLG | ENSPTRP00000017648 | ENSPTRP00000032051 | Complement component 3. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.948 |
| C3 | SERPINC1 | ENSPTRP00000017648 | ENSPTRP00000002829 | Complement component 3. | Serpin family C member 1; Belongs to the serpin family. | 0.466 |
| F3 | HRG | ENSPTRP00000040007 | ENSPTRP00000027038 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Histidine rich glycoprotein. | 0.428 |
| F3 | PLAT | ENSPTRP00000040007 | ENSPTRP00000034599 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Plasminogen activator; Belongs to the peptidase S1 family. | 0.790 |
| F3 | PLAU | ENSPTRP00000040007 | ENSPTRP00000004595 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Plasminogen activator, urokinase. | 0.726 |
| F3 | PLG | ENSPTRP00000040007 | ENSPTRP00000032051 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.848 |
| F3 | SERPINC1 | ENSPTRP00000040007 | ENSPTRP00000002829 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Serpin family C member 1; Belongs to the serpin family. | 0.766 |
| F3 | SERPINE1 | ENSPTRP00000040007 | ENSPTRP00000033420 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Serpin family E member 1; Belongs to the serpin family. | 0.671 |
| F3 | SERPINF2 | ENSPTRP00000040007 | ENSPTRP00000090784 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Serpin family F member 2; Belongs to the serpin family. | 0.562 |
| FGA | C3 | ENSPTRP00000028386 | ENSPTRP00000017648 | Fibrinogen alpha chain. | Complement component 3. | 0.762 |
| FGA | FGB | ENSPTRP00000028386 | ENSPTRP00000028385 | Fibrinogen alpha chain. | Fibrinogen beta chain. | 0.999 |
| FGA | HRG | ENSPTRP00000028386 | ENSPTRP00000027038 | Fibrinogen alpha chain. | Histidine rich glycoprotein. | 0.894 |
| FGA | PLAT | ENSPTRP00000028386 | ENSPTRP00000034599 | Fibrinogen alpha chain. | Plasminogen activator; Belongs to the peptidase S1 family. | 0.759 |
| FGA | PLAU | ENSPTRP00000028386 | ENSPTRP00000004595 | Fibrinogen alpha chain. | Plasminogen activator, urokinase. | 0.615 |
| FGA | PLG | ENSPTRP00000028386 | ENSPTRP00000032051 | Fibrinogen alpha chain. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.931 |
| FGA | SERPINC1 | ENSPTRP00000028386 | ENSPTRP00000002829 | Fibrinogen alpha chain. | Serpin family C member 1; Belongs to the serpin family. | 0.961 |
| FGA | SERPINE1 | ENSPTRP00000028386 | ENSPTRP00000033420 | Fibrinogen alpha chain. | Serpin family E member 1; Belongs to the serpin family. | 0.433 |
| FGA | SERPINF2 | ENSPTRP00000028386 | ENSPTRP00000090784 | Fibrinogen alpha chain. | Serpin family F member 2; Belongs to the serpin family. | 0.821 |
