STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGR3Anterior gradient 3, protein disulphide isomerase family member. (166 aa)    
Predicted Functional Partners:
LYPD3
LYPD3 isoform 1.
    
 
 0.691
TMX1
Thioredoxin-related transmembrane protein 1.
      
 0.631
PDIA4
Protein disulfide-isomerase A4.
      
 0.602
PDIA4-2
Protein disulfide isomerase family A member 4.
      
 0.602
ERP29
Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase.
      
 0.593
ERP27
Endoplasmic reticulum protein 27.
      
 0.577
PDILT
PDILT isoform 1.
      
 0.572
PDIA5
Protein disulfide isomerase family A member 5.
      
 0.520
ERP44
Endoplasmic reticulum protein 44.
      
 0.511
PDIA3
Protein disulfide-isomerase.
      
 0.511
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.