| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDA | DPYD | ENSPTRP00000000499 | ENSPTRP00000001697 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.501 |
| CDA | NT5C | ENSPTRP00000000499 | ENSPTRP00000086413 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5', 3'-nucleotidase, cytosolic. | 0.912 |
| CDA | NT5E | ENSPTRP00000000499 | ENSPTRP00000031424 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | 0.920 |
| CDA | TYMP | ENSPTRP00000000499 | ENSPTRP00000040056 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine phosphorylase. | 0.991 |
| CDA | UCK1 | ENSPTRP00000000499 | ENSPTRP00000082262 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.982 |
| CDA | UCK2 | ENSPTRP00000000499 | ENSPTRP00000002709 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.977 |
| CDA | UCKL1 | ENSPTRP00000000499 | ENSPTRP00000073925 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.979 |
| CDA | UMPS | ENSPTRP00000000499 | ENSPTRP00000026399 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine monophosphate synthetase. | 0.517 |
| CDA | UPP1 | ENSPTRP00000000499 | ENSPTRP00000032766 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.983 |
| CDA | UPP2 | ENSPTRP00000000499 | ENSPTRP00000021460 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.985 |
| DPYD | CDA | ENSPTRP00000001697 | ENSPTRP00000000499 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.501 |
| DPYD | NT5E | ENSPTRP00000001697 | ENSPTRP00000031424 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | 0.648 |
| DPYD | TYMP | ENSPTRP00000001697 | ENSPTRP00000040056 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Thymidine phosphorylase. | 0.980 |
| DPYD | UCKL1 | ENSPTRP00000001697 | ENSPTRP00000073925 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.404 |
| DPYD | UMPS | ENSPTRP00000001697 | ENSPTRP00000026399 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine monophosphate synthetase. | 0.997 |
| DPYD | UPP1 | ENSPTRP00000001697 | ENSPTRP00000032766 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.963 |
| DPYD | UPP2 | ENSPTRP00000001697 | ENSPTRP00000021460 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.967 |
| NT5C | CDA | ENSPTRP00000086413 | ENSPTRP00000000499 | 5', 3'-nucleotidase, cytosolic. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.912 |
| NT5C | NT5E | ENSPTRP00000086413 | ENSPTRP00000031424 | 5', 3'-nucleotidase, cytosolic. | 5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. | 0.937 |
| NT5C | TYMP | ENSPTRP00000086413 | ENSPTRP00000040056 | 5', 3'-nucleotidase, cytosolic. | Thymidine phosphorylase. | 0.932 |
