STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAT2Linker for activation of T cells family member 2. (243 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
    
 0.804
SYK
Tyrosine-protein kinase.
   
 
 0.650
GRAP2
GRB2 related adaptor protein 2.
    
 0.648
LYN
Tyrosine-protein kinase.
   
 
 0.622
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
     
 0.621
LAT
Linker for activation of T cells.
      
 0.619
LCP2
Lymphocyte cytosolic protein 2.
   
  
 0.602
LAX1
Lymphocyte transmembrane adaptor 1.
  
   
 0.585
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 
 0.581
SHC1
SHC (Src homology 2 domain containing) transforming protein 1.
     
 0.532
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.