GNAI1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GNAI1

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. (422 aa)

Predicted Functional Partners:

GNB1

0.998

GNG2

0.995

LPAR1

0.993

DRD2

0.993

S1PR1

0.987

PTGER3

0.987

GABBR2

0.986

GNAI3

0.985

MTNR1A

0.985

MTNR1B

0.985

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD2	GABBR2	ENSPTRP00000069610	ENSPTRP00000046269	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Gamma-aminobutyric acid type B receptor subunit 2.	0.503
DRD2	GNAI1	ENSPTRP00000069610	ENSPTRP00000071974	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.993
DRD2	GNAI3	ENSPTRP00000069610	ENSPTRP00000001821	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.935
DRD2	GNB1	ENSPTRP00000069610	ENSPTRP00000067330	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.976
DRD2	GNG2	ENSPTRP00000069610	ENSPTRP00000065345	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.951
GABBR2	DRD2	ENSPTRP00000046269	ENSPTRP00000069610	Gamma-aminobutyric acid type B receptor subunit 2.	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	0.503
GABBR2	GNAI1	ENSPTRP00000046269	ENSPTRP00000071974	Gamma-aminobutyric acid type B receptor subunit 2.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	0.986
GABBR2	GNAI3	ENSPTRP00000046269	ENSPTRP00000001821	Gamma-aminobutyric acid type B receptor subunit 2.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.962
GABBR2	GNB1	ENSPTRP00000046269	ENSPTRP00000067330	Gamma-aminobutyric acid type B receptor subunit 2.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.938
GABBR2	GNG2	ENSPTRP00000046269	ENSPTRP00000065345	Gamma-aminobutyric acid type B receptor subunit 2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.947
GNAI1	DRD2	ENSPTRP00000071974	ENSPTRP00000069610	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	0.993
GNAI1	GABBR2	ENSPTRP00000071974	ENSPTRP00000046269	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Gamma-aminobutyric acid type B receptor subunit 2.	0.986
GNAI1	GNAI3	ENSPTRP00000071974	ENSPTRP00000001821	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.	0.985
GNAI1	GNB1	ENSPTRP00000071974	ENSPTRP00000067330	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.998
GNAI1	GNG2	ENSPTRP00000071974	ENSPTRP00000065345	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.995
GNAI1	LPAR1	ENSPTRP00000071974	ENSPTRP00000063334	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.993
GNAI1	MTNR1A	ENSPTRP00000071974	ENSPTRP00000028581	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	T0111385 isoform 1.	0.985
GNAI1	MTNR1B	ENSPTRP00000071974	ENSPTRP00000047712	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family.	0.985
GNAI1	PTGER3	ENSPTRP00000071974	ENSPTRP00000075104	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Prostaglandin E receptor 3.	0.987
GNAI1	S1PR1	ENSPTRP00000071974	ENSPTRP00000061397	Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1.	Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.987