STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASB4Ankyrin repeat and SOCS box containing 4. (426 aa)    
Predicted Functional Partners:
CHRAC1
Chromatin accessibility complex subunit 1.
      
 0.796
TRAPPC9
Trafficking protein particle complex 9.
    
 
 0.737
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3.
    
 
 0.732
GRB10
Growth factor receptor-bound protein 10.
    
 
 0.727
COPG2
Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.712
CUL5
CUL5 isoform 1; Belongs to the cullin family.
    
 0.657
COPRS
Coordinator of PRMT5 and differentiation stimulator.
      
 0.651
COMMD1
Copper metabolism (Murr1) domain containing 1.
    
 0.637
RAB11FIP4
RAB11 family interacting protein 4.
      
 0.621
CISH
Cytokine inducible SH2 containing protein.
     
 0.621
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.