STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCN1Chloride channel protein. (989 aa)    
Predicted Functional Partners:
MBNL3
Muscleblind like splicing regulator 3.
      
 0.772
CELF1
CELF1 isoform 5.
      
 0.767
MBNL2
MBNL2 isoform 2.
      
 0.748
ABLIM1
Actin binding LIM protein 1.
      
 0.724
DMPK
Dystrophia myotonica-protein kinase.
      
 0.693
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
  
 0.688
CELF3
CELF3 isoform 2.
      
 0.677
CELF4
CUGBP Elav-like family member 4.
      
 0.654
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
   
 0.651
MBNL1
Muscleblind like splicing regulator 1.
      
 0.642
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.