CUL1 protein (Pan troglodytes) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

CUL1

CUL1 isoform 1; Belongs to the cullin family. (776 aa)

Predicted Functional Partners:

RBX1

0.999

SKP1

0.999

SKP2

0.997

BTRC

0.996

CAND1

0.991

CDKN1B

0.989

CKS1B

0.979

FBXW7

0.974

CD4

0.969

FBXO5

0.967

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	CAND1	ENSPTRP00000077054	ENSPTRP00000008818	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin-associated and neddylation-dissociated 1.	0.642
BTRC	CD4	ENSPTRP00000077054	ENSPTRP00000054833	Beta-transducin repeat containing E3 ubiquitin protein ligase.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.900
BTRC	CUL1	ENSPTRP00000077054	ENSPTRP00000033967	Beta-transducin repeat containing E3 ubiquitin protein ligase.	CUL1 isoform 1; Belongs to the cullin family.	0.996
BTRC	FBXO5	ENSPTRP00000077054	ENSPTRP00000031946	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 5.	0.983
BTRC	FBXW7	ENSPTRP00000077054	ENSPTRP00000028353	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 7.	0.965
BTRC	RBX1	ENSPTRP00000077054	ENSPTRP00000024839	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Ring-box 1, E3 ubiquitin protein ligase.	0.999
BTRC	SKP1	ENSPTRP00000077054	ENSPTRP00000069790	Beta-transducin repeat containing E3 ubiquitin protein ligase.	T0093123 isoform 1; Belongs to the SKP1 family.	0.999
BTRC	SKP2	ENSPTRP00000077054	ENSPTRP00000028804	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase-associated protein 2 (P45).	0.977
CAND1	BTRC	ENSPTRP00000008818	ENSPTRP00000077054	Cullin-associated and neddylation-dissociated 1.	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.642
CAND1	CUL1	ENSPTRP00000008818	ENSPTRP00000033967	Cullin-associated and neddylation-dissociated 1.	CUL1 isoform 1; Belongs to the cullin family.	0.991
CAND1	FBXW7	ENSPTRP00000008818	ENSPTRP00000028353	Cullin-associated and neddylation-dissociated 1.	F-box and WD repeat domain containing 7.	0.637
CAND1	RBX1	ENSPTRP00000008818	ENSPTRP00000024839	Cullin-associated and neddylation-dissociated 1.	Ring-box 1, E3 ubiquitin protein ligase.	0.993
CAND1	SKP1	ENSPTRP00000008818	ENSPTRP00000069790	Cullin-associated and neddylation-dissociated 1.	T0093123 isoform 1; Belongs to the SKP1 family.	0.859
CAND1	SKP2	ENSPTRP00000008818	ENSPTRP00000028804	Cullin-associated and neddylation-dissociated 1.	S-phase kinase-associated protein 2 (P45).	0.814
CD4	BTRC	ENSPTRP00000054833	ENSPTRP00000077054	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Beta-transducin repeat containing E3 ubiquitin protein ligase.	0.900
CD4	CUL1	ENSPTRP00000054833	ENSPTRP00000033967	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	CUL1 isoform 1; Belongs to the cullin family.	0.969
CD4	RBX1	ENSPTRP00000054833	ENSPTRP00000024839	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ring-box 1, E3 ubiquitin protein ligase.	0.906
CD4	SKP1	ENSPTRP00000054833	ENSPTRP00000069790	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	T0093123 isoform 1; Belongs to the SKP1 family.	0.955
CDKN1B	CKS1B	ENSPTRP00000008044	ENSPTRP00000002352	Cyclin-dependent kinase inhibitor 1B (P27, Kip1).	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.931
CDKN1B	CUL1	ENSPTRP00000008044	ENSPTRP00000033967	Cyclin-dependent kinase inhibitor 1B (P27, Kip1).	CUL1 isoform 1; Belongs to the cullin family.	0.989