STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EZH2-2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)    
Predicted Functional Partners:
EED
Embryonic ectoderm development.
   
 0.987
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.985
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  
 0.971
AEBP2
AE binding protein 2.
   
 0.964
DNMT3B
DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
 0.951
PHF1
PHD finger protein 1.
   
 0.949
LOC468384
Polycomb protein SUZ12.
   
 0.949
ENSPTRP00000092184
annotation not available
   
 0.949
JARID2
Jumonji and AT-rich interaction domain containing 2.
   
 0.945
MTF2
Metal response element binding transcription factor 2.
   
 0.938
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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