STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (182 aa)    
Predicted Functional Partners:
ITSN2
ITSN2 isoform 1.
   
 0.789
TSC2
Tuberous sclerosis 2.
    
 0.769
TSC1
TSC complex subunit 1.
   
 0.746
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.743
ITSN1
ITSN1 isoform 4.
    
 0.681
ITSN1-2
ITSN1 isoform 7.
    
 0.681
RPTOR
Regulatory associated protein of MTOR, complex 1.
    
 0.664
LOC104003639
Guanine nucleotide-binding protein G(s) subunit alpha.
   
 0.659
MLST8
MLST8 isoform 3.
    
 0.612
LIM2
Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.
  
 0.584
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.