| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DEFA5 | DEFB1 | ENSPTRP00000072107 | ENSPTRP00000034184 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | 0.812 |
| DEFA5 | DEFB103A | ENSPTRP00000072107 | ENSPTRP00000034200 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family. | 0.974 |
| DEFA5 | DEFB104 | ENSPTRP00000072107 | ENSPTRP00000034195 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | Beta-defensin 104A; Has antimicrobial activity; Belongs to the beta-defensin family. | 0.716 |
| DEFA5 | DEFB105A | ENSPTRP00000072107 | ENSPTRP00000034193 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family. | 0.725 |
| DEFA5 | DEFB106A | ENSPTRP00000072107 | ENSPTRP00000034194 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. | 0.728 |
| DEFA5 | DEFB107A | ENSPTRP00000072107 | ENSPTRP00000034191 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | Beta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family. | 0.723 |
| DEFA5 | DEFB4A | ENSPTRP00000072107 | ENSPTRP00000072908 | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | Beta-defensin 4A; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells; Belongs to the beta-defensin family. LAP/TAP subfamily. | 0.954 |
| DEFB1 | DEFA5 | ENSPTRP00000034184 | ENSPTRP00000072107 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | 0.812 |
| DEFB1 | DEFB103A | ENSPTRP00000034184 | ENSPTRP00000034200 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family. | 0.984 |
| DEFB1 | DEFB104 | ENSPTRP00000034184 | ENSPTRP00000034195 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 104A; Has antimicrobial activity; Belongs to the beta-defensin family. | 0.806 |
| DEFB1 | DEFB105A | ENSPTRP00000034184 | ENSPTRP00000034193 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family. | 0.947 |
| DEFB1 | DEFB106A | ENSPTRP00000034184 | ENSPTRP00000034194 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. | 0.928 |
| DEFB1 | DEFB107A | ENSPTRP00000034184 | ENSPTRP00000034191 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family. | 0.952 |
| DEFB1 | DEFB118 | ENSPTRP00000034184 | ENSPTRP00000067247 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 118; Has antibacterial activity; Belongs to the beta-defensin family. | 0.844 |
| DEFB1 | DEFB119 | ENSPTRP00000034184 | ENSPTRP00000071557 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | 0.828 |
| DEFB1 | DEFB129 | ENSPTRP00000034184 | ENSPTRP00000022492 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 129; Has antibacterial activity; Belongs to the beta-defensin family. | 0.788 |
| DEFB1 | DEFB4A | ENSPTRP00000034184 | ENSPTRP00000072908 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | Beta-defensin 4A; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells; Belongs to the beta-defensin family. LAP/TAP subfamily. | 0.985 |
| DEFB103A | DEFA5 | ENSPTRP00000034200 | ENSPTRP00000072107 | Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family. | Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family. | 0.974 |
| DEFB103A | DEFB1 | ENSPTRP00000034200 | ENSPTRP00000034184 | Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family. | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. | 0.984 |
| DEFB103A | DEFB104 | ENSPTRP00000034200 | ENSPTRP00000034195 | Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family. | Beta-defensin 104A; Has antimicrobial activity; Belongs to the beta-defensin family. | 0.820 |
