DEFB106A protein (Pan troglodytes) - STRING interaction network

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DEFB106A

Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. (65 aa)

Predicted Functional Partners:

DEFB107A

0.923

DEFB105A

0.914

DEFB104

0.869

DEFB1

0.867

DEFB103A

0.867

DEFB108B

0.835

SPAG11B

0.831

DEFA5

0.734

DEFB110

0.612

LOC107973208

0.599

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEFA5	DEFB1	ENSPTRP00000072107	ENSPTRP00000034184	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	0.853
DEFA5	DEFB103A	ENSPTRP00000072107	ENSPTRP00000034200	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family.	0.972
DEFA5	DEFB104	ENSPTRP00000072107	ENSPTRP00000034195	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Beta-defensin 104A; Has antimicrobial activity; Belongs to the beta-defensin family.	0.715
DEFA5	DEFB105A	ENSPTRP00000072107	ENSPTRP00000034193	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family.	0.732
DEFA5	DEFB106A	ENSPTRP00000072107	ENSPTRP00000034194	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2.	0.734
DEFA5	DEFB107A	ENSPTRP00000072107	ENSPTRP00000034191	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Beta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family.	0.726
DEFA5	DEFB108B	ENSPTRP00000072107	ENSPTRP00000006911	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Beta-defensin 108B; Has antibacterial activity; Belongs to the beta-defensin family.	0.595
DEFA5	LOC107973208	ENSPTRP00000072107	ENSPTRP00000079419	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Neutrophil defensin 1; Has antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane (By similarity); Belongs to the alpha-defensin family.	0.921
DEFA5	SPAG11B	ENSPTRP00000072107	ENSPTRP00000034197	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	Sperm-associated antigen 11; Belongs to the SPAG11 family.	0.446
DEFB1	DEFA5	ENSPTRP00000034184	ENSPTRP00000072107	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	0.853
DEFB1	DEFB103A	ENSPTRP00000034184	ENSPTRP00000034200	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family.	0.985
DEFB1	DEFB104	ENSPTRP00000034184	ENSPTRP00000034195	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 104A; Has antimicrobial activity; Belongs to the beta-defensin family.	0.817
DEFB1	DEFB105A	ENSPTRP00000034184	ENSPTRP00000034193	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family.	0.923
DEFB1	DEFB106A	ENSPTRP00000034184	ENSPTRP00000034194	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2.	0.867
DEFB1	DEFB107A	ENSPTRP00000034184	ENSPTRP00000034191	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family.	0.921
DEFB1	DEFB108B	ENSPTRP00000034184	ENSPTRP00000006911	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 108B; Has antibacterial activity; Belongs to the beta-defensin family.	0.742
DEFB1	DEFB110	ENSPTRP00000034184	ENSPTRP00000049999	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 110; Has antibacterial activity; Belongs to the beta-defensin family.	0.466
DEFB1	LOC107973208	ENSPTRP00000034184	ENSPTRP00000079419	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Neutrophil defensin 1; Has antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane (By similarity); Belongs to the alpha-defensin family.	0.729
DEFB1	SPAG11B	ENSPTRP00000034184	ENSPTRP00000034197	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Sperm-associated antigen 11; Belongs to the SPAG11 family.	0.495
DEFB103A	DEFA5	ENSPTRP00000034200	ENSPTRP00000072107	Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family.	Defensin-5; Has antimicrobial activity against Gram-negative and Gram- positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing (By similarity); Belongs to the alpha-defensin family.	0.972