STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK2Docking protein 2. (412 aa)    
Predicted Functional Partners:
IL2RG
IL2RG isoform 1.
   
  
 0.828
LCK
Tyrosine-protein kinase.
   
 0.825
RASA1
RAS p21 protein activator (GTPase activating protein) 1.
   
 
 0.812
CCND3
CCND3 isoform 1; Belongs to the cyclin family.
   
  
 0.772
NCK1
Cytoplasmic protein.
    
 
 0.738
TEK
TEK receptor tyrosine kinase.
    
 0.733
GRB2
Growth factor receptor-bound protein 2.
    
 0.658
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
    
 0.636
CSK
Tyrosine-protein kinase.
   
 0.615
SHC1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.614
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.