STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)    
Predicted Functional Partners:
GPX3
GPX3 isoform 3.
  
 0.989
GPX6
Glutathione peroxidase 6 precursor.
  
 0.989
GPX2
GPX2 isoform 4.
  
 0.989
GPX7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.987
GPX8
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.987
GPX1
Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown.
  
 0.979
GPX4
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.975
PRDX6
PRDX6 isoform 1.
  
 0.955
GSS
Glutathione synthetase.
    
 0.945
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
   
 
 0.945
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.