RUNX1T1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFA2T3	HDAC1	ENSPTRP00000069578	ENSPTRP00000075891	CBFA2/RUNX1 translocation partner 3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.574
CBFA2T3	LOC748850	ENSPTRP00000069578	ENSPTRP00000067224	CBFA2/RUNX1 translocation partner 3.	HDAC2 isoform 9.	0.574
CBFA2T3	NCOR1	ENSPTRP00000069578	ENSPTRP00000075557	CBFA2/RUNX1 translocation partner 3.	Nuclear receptor corepressor 1.	0.717
CBFA2T3	NCOR2	ENSPTRP00000069578	ENSPTRP00000088620	CBFA2/RUNX1 translocation partner 3.	Nuclear receptor corepressor 2.	0.648
CBFA2T3	PRDM14	ENSPTRP00000069578	ENSPTRP00000086310	CBFA2/RUNX1 translocation partner 3.	PR/SET domain 14.	0.838
CBFA2T3	RUNX1	ENSPTRP00000069578	ENSPTRP00000092866	CBFA2/RUNX1 translocation partner 3.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.803
CBFA2T3	RUNX1T1	ENSPTRP00000069578	ENSPTRP00000075111	CBFA2/RUNX1 translocation partner 3.	RUNX1 translocation partner 1.	0.809
CBFA2T3	TCF12	ENSPTRP00000069578	ENSPTRP00000012156	CBFA2/RUNX1 translocation partner 3.	Transcription factor 12.	0.743
CBFA2T3	ZBTB16	ENSPTRP00000069578	ENSPTRP00000007389	CBFA2/RUNX1 translocation partner 3.	Zinc finger and BTB domain containing 16.	0.653
HDAC1	CBFA2T3	ENSPTRP00000075891	ENSPTRP00000069578	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	CBFA2/RUNX1 translocation partner 3.	0.574
HDAC1	LOC748850	ENSPTRP00000075891	ENSPTRP00000067224	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	HDAC2 isoform 9.	0.900
HDAC1	NCOR1	ENSPTRP00000075891	ENSPTRP00000075557	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor corepressor 1.	0.965
HDAC1	NCOR2	ENSPTRP00000075891	ENSPTRP00000088620	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor corepressor 2.	0.972
HDAC1	RUNX1	ENSPTRP00000075891	ENSPTRP00000092866	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.981
HDAC1	RUNX1T1	ENSPTRP00000075891	ENSPTRP00000075111	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	RUNX1 translocation partner 1.	0.819
HDAC1	SPI1	ENSPTRP00000075891	ENSPTRP00000084012	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Spi-1 proto-oncogene.	0.687
HDAC1	ZBTB16	ENSPTRP00000075891	ENSPTRP00000007389	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Zinc finger and BTB domain containing 16.	0.811
LOC748850	CBFA2T3	ENSPTRP00000067224	ENSPTRP00000069578	HDAC2 isoform 9.	CBFA2/RUNX1 translocation partner 3.	0.574
LOC748850	HDAC1	ENSPTRP00000067224	ENSPTRP00000075891	HDAC2 isoform 9.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.900
LOC748850	NCOR1	ENSPTRP00000067224	ENSPTRP00000075557	HDAC2 isoform 9.	Nuclear receptor corepressor 1.	0.835